Born Odysseas Mazarakis Arampatzoglou, he studied at Halki Theological School and then moved to Lausanne where he continued his studies in Philosophy and Law. He served repeatedly as a member of the Holy Synod of the Ecumenical Patriarchate. Being a linguistc and able to speak fluently in eight languages he served many times as representative of the Ecumenical Patriarchate in various ecclesiastical and scientific conferences.
The year 1953 was declared Honorary Doctor of School of Theology at the University of Thessaloniki. He wrote numerous studies and articles. He worked mainly on the ecclesiastical history of the Ecumenical Patriarchate. It is said that he died after brutal beatings during the Istanbul pogrom of 6th to 7th of September in 1955.